Successful proposals will contribute to the EU Initiative on Biotech and Biomanufacturing, the implementation of the EU Bioeconomy Strategy and its action plan, the Circular Economy Action Plan, the EU Zero pollution ambition for a toxic-free environment under the Chemicals Strategy for Sustainability and the Zero Pollution Action Plan, as well as the EU Industrial strategy.
Projects results are expected to contribute to the following expected outcomes:
- Increased scale-up potential and sustainability of biotech processes to produce bio-based chemicals, materials and/or ingredients, contributing to increased competitiveness of industrial biotech in EU.
- Increased and stable productivity and selectivity compared to benchmark batch/fed-batch process(es), if available at industrial scale.
- Purity of end-product(s) in line with application requirements.
Many bio-based chemicals/products are manufactured via biotech batch or fed-batch processes at commercial scale, which despite being easier to be controlled and scaled-up, often result into lower productivity, higher equipment downtime and increased costs. Continuous biotech processes could represent promising emerging alternatives in biorefineries targeting high productivity and reduced costs. Despite having achieved significant advancements in some cases, there are still challenges to overcome towards scaling-up, such as: contamination risks, genetic instability of cells, maintaining simultaneously high production titer, productivity and yield,
...
